Literature summary extracted from

Khamis, Z.I.; Iczkowski, K.A.; Man, Y.G.; Bou-Dargham, M.J.; Sang, Q.X.
Evidence for a proapoptotic role of matrix metalloproteinase-26 in human prostate cancer cells and tissues (2016), J. Cancer, 7, 80-87 .

Application

EC Number	Application	Comment	Organism
3.4.24.B7	medicine	MMP-26 expression levels in androgen-repressed human prostate cancer cells, transfected with sense or anti-sense MMP-26 cDNA, and in benign, neoplastic, and invasive prostate cancer tissues are directly correlated with those of the pro-apoptotic marker Bax. The MMP-26 protein levels are upregulated in high grade prostate intraepithelial neoplasia and decrease during the course of disease progression	Homo sapiens

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.4.24.B7	Homo sapiens	Q9NRE1	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
3.4.24.B7	prostate gland	-	Homo sapiens	-
3.4.24.B7	prostate gland cancer cell	androgen-repressed prostate cancer cell	Homo sapiens	-

General Information

EC Number	General Information	Comment	Organism
3.4.24.B7	physiological function	MMP-26 expression levels in androgen-repressed human prostate cancer cells, transfected with sense or anti-sense MMP-26 cDNA, and in benign, neoplastic, and invasive prostate cancer tissues are directly correlated with those of the pro-apoptotic marker Bax. The MMP-26 protein levels are upregulated in high grade prostate intraepithelial neoplasia and decrease during the course of disease progression	Homo sapiens

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Release 2023.1 (January 2023)